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cenobamate will increase the level or result of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Observe Closely. Consider a dose reduction of CYP2C19 substrates, as clinically proper, when utilised concomitantly with cenobamate.diazepam decreases levels of acetaminophen rectal by escalating metabolism. Insignificant/Importan